منابع مشابه
ECG changes of cardiac origin in elderly patients with traumatic brain injury
Background: Simultaneous electrocardiographic (ECG) changes are seen in hemorrhagic brain events even in the absence of associated myocardial infarction (MI). This study was designed to assess the role of ECG changes to predict true MI in patients with hemorrhagic brain trauma. Methods: Data of 153 patients with traumatic brain injury and concomitant ECG changes were recorded. Enzyme study w...
متن کاملOrigin of cardiac fibroblasts and the role of periostin.
Cardiac fibroblasts are the most populous nonmyocyte cell type within the mature heart and are required for extracellular matrix synthesis and deposition, generation of the cardiac skeleton, and to electrically insulate the atria from the ventricles. Significantly, cardiac fibroblasts have also been shown to play an important role in cardiomyocyte growth and expansion of the ventricular chamber...
متن کاملThe origin of fibroblasts and mechanism of cardiac fibrosis.
Fibroblasts are at the heart of cardiac function and are the principal determinants of cardiac fibrosis. Nevertheless, cardiac fibroblasts remain poorly characterized in molecular terms. Evidence is evolving that the cardiac fibroblast is a highly heterogenic cell population, and that such heterogeneity is caused by the distinct origins of fibroblasts in the heart. Cardiac fibroblasts can deriv...
متن کاملWnt1/bcatenin injury response activates the epicardium and cardiac fibroblasts to promote cardiac repair
Jinzhu Duan, Costin Gherghe, Dianxin Liu, Eric Hamlett, Luxman Srikantha, Laurel Rodgers, Jenna N Regan, Mauricio Rojas, Monte Willis, Andrew Leask, Mark Majesky and Arjun Deb* Department of Medicine, McAllister Heart Institute and Lineberger Comprehensive Cancer Center, University of North Carolina, Chapel Hill, NC, USA, Department of Cell and Molecular Physiology, McAllister Heart Institute a...
متن کاملWnt1/βcatenin injury response activates the epicardium and cardiac fibroblasts to promote cardiac repair.
Wnts are required for cardiogenesis but the role of specific Wnts in cardiac repair remains unknown. In this report, we show that a dynamic Wnt1/βcatenin injury response activates the epicardium and cardiac fibroblasts to promote cardiac repair. Acute ischaemic cardiac injury upregulates Wnt1 that is initially expressed in the epicardium and subsequently by cardiac fibroblasts in the region of ...
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ژورنال
عنوان ژورنال: Current Opinion in Physiology
سال: 2018
ISSN: 2468-8673
DOI: 10.1016/j.cophys.2017.08.002